WebValidated in IHC and tested in Mouse, Human. Cited in 4 publication(s). Independently reviewed in 3 review(s). Immunogen corresponding to synthetic peptide. ... Further … WebAgrin, a multidomain proteoglycan and neurotrypsin, a neuronal serine protease, are important for forming (neuromuscular) synapses. Proteolytical activity of neurotrypsin produces a C-terminal...
The elongated rod-like particle of full-length agrin is …
WebBackground: Serum concentrations of the C-terminal fragment of agrin (CAF), a component of the neuromuscular junction (NMJ), are elevated in older community-dwellers with sarcopenia. Whether CAF may be used as a marker for muscle wasting in the presence of NMJ mechanical damage is presently unknown. The present study was undertaken to … WebThe muscle isoform of agrin harbors A and B regions near its C-terminal. Two reports describe a CMS caused by defects in agrin. Two reports describe a CMS caused by … how to install interlocking wall tile
11603 - Gene ResultAgrn agrin [ (house mouse)] - National …
WebThe C-terminal region of agrin has been most extensively studied, since this is the region that is sufficient to induce the aggregation of AChRs. The number of other molecules that interact with agrin at the neuromuscular junction is extensive. The N-terminal region of agrin has been shown to bind to laminin. WebApr 1, 2003 · This contrasts with previous observations in which it was clearly shown that nerve-derived, glycosylated agrin, as well as non-glycosylated, carboxy-terminal agrin fragments, require inserts at ... WebMay 22, 2014 · The cause of fragmentation of NMJs in aged and dystrophic muscle is rather unclear, but there are different possible explanations. First, it is conceivable that fragmentation of NMJs is due to degeneration of … how to install in terminal