WebCystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well. Tissue specificity Expressed in … Cystatin-SN is a protein that in humans is encoded by the CST1 gene. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three … See more • The MEROPS online database for peptidases and their inhibitors: I25.010 • Human CST1 genome location and CST1 gene details page in the UCSC Genome Browser. See more • Brown WM, Dziegielewska KM (1997). "Friends and relations of the cystatin superfamily--new members and their evolution". … See more

CST1 cystatin SN - NIH Genetic Testing Registry (GTR) - NCBI

WebJul 1, 2024 · The accuracy of Cystatin SN together with local sIgE and loss of smell to diagnose NARES was up to 0.987 (sensitivity, 100%; specificity, 93.1%). Conclusions Cystatin SN with local sIgE and loss ... WebMar 8, 2024 · Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well. Tissue specificity Expressed in submandibular and sublingual saliva but … charity schmitt nevada

National Center for Biotechnology Information

WebAllergen source-derived proteases are a critical factor in the formation and development of asthma. The cysteine protease activity of house dust mite (HDM) disrupts the epithelial … WebCystatin S and SN can also be expressed in tears, urine and seminal fluid. Cystatin C is a related protein which is expressed in brain, thymus, ovary, epididymis and vas deferens. … WebCystatin (CST) was first isolated from egg white by Anastasi et al using affinity chromatography, with the feature of inhibitory effect on cysteine protease. 9 CST1 gene is located on chromosome 20p11.21 and encodes cystatin SN protein that belongs to the second subfamily of cystatin superfamily, which includes 7 exocrine proteins: Cystatin … harry hiestand football coach