WebOct 19, 2024 · The primary endpoint was ORR assessed by independent radiological review committee (IRRC) per RECIST v1.1; confirmation of complete response and partial response was required after 28 days. Web2 days ago · The primary endpoint was changed from 2-year PFS rate to ORR following a discussion involving all principal investigators in this investigator-initiated trial. The original primary endpoint, 2-year PFS rate, was kept as the key secondary endpoint.
ESMO Asia 2024 Congress OncologyPRO
WebSep 29, 2024 · Conclusion: According to the arm-level and trial level-analysis, we suggest that in phase II and III trials of targeted therapy and immunotherapy for NSCLC patients: … WebMay 28, 2024 · Results: A total of 36 drugs received primary approval for the treatment of solid tumors between 2015 and 2024. Of the 40 supporting trials, ORR was the primary endpoint for 21 (52.5%), progression-free survival for 13 (32.5%), and overall survival for 2 (5.0%). ORR was evaluated in 35 of the 40 trials (87.5%). reimbursement gas mileage 2021
Phase II DESTINY-Gastric01 trial of Enhertu versus ... - AstraZeneca
WebApr 14, 2024 · The primary endpoint was the investigator-assessed overall response rate (ORR) (see the section of study endpoints in Methods).As a supportive analysis defined in the study protocol, ORR was also ... Webline, based on ORR and DOR in single arm trial KN-052 June 2024 • eDMC Finding & Restriction of 1. st ... Primary endpoint: BICR-ORR in ITT and PD-L1-high. Disease … WebJun 26, 2024 · In a single-arm trial (NCT01874873) in 55 evaluable patients with medullary thyroid carcinoma treated with anlotinib, the mean PFS was 12.8 months (median PFS still not reached) (primary endpoint), ORR was 48.28% and … reimbursement gas mileage